The Advanced Research Projects Agency for Health (ARPA-H) is a federal agency to improve the U.S. government’s ability to speed biomedical and health research. Public Law 117-103 was enacted on March 15, 2022, authorizing the establishment of ARPA-H within the U.S. Department of Health and Human Services.

ARPA-H will:

• Speed application and implementation of health breakthroughs to serve all patients

• Foster breakthroughs across various levels — from the molecular to the societal 

• Build capabilities and platforms to revolutionize prevention, treatment, and cures in a range of diseases

• Support “use-driven” ideas focused on solving practical problems that advance equity and rapidly transform breakthroughs into tangible solutions for all patients.

• Focus on multiple time-limited projects with different approaches to achieve a quantifiable goal.

• Use a stage-gate process, with defined metrics, and inject accountability through meeting these metrics.

• Overcome market failures through critical solutions or incentives

• Use the Defense Advanced Research Projects Agency (DARPA) as a model to establish a culture of championing innovative ideas in health and medicine.