The Specific Aims document is one of the most important parts of a NIH grants submission – it’s also one of the most difficult to write. This may be the only document read by reviewers and it’s the one generally used to assign study section members. The Aims page needs to be written as a standalone document; and it must answer the following questions: What’s the problem, why should we care and how will you fix it?
GuidanceHow to: | Here is some recommend guidance about the Specific Aims: Specific Aims should provide the conceptual framework, a partnership, between you and the assigned reviewer who advocates for your proposal. Rest of reviewers will be reviewing your proposal likely in “real time” focusing on Title, Summary/Abstract, Specific Aims, Significance and Innovation sections The Aims becomes a template for the rest of the Research Plan Include everything about proposal that is exciting and compelling but without the detail Logic must be clear and compelling and must readily flow from each component Recommend starting with an outline to ensure flow and eliminate unnecessary detail. Have an interest-grabbing opening sentence that establishes the relevance of the proposal, helps accomplish NIH goals, is not obvious Current knowledge component brings less knowledgeable reviewers up to speed on your topic and sets up the gab in knowledge or unmet need. Only key citations should be included The Gap in Knowledge/Unmet need critical to the downstream flow of logic, must tie back to the current knowledge The “What, Why, Who” paragraph takes reviewer from broadest to narrowest focus of application; has a credible long-term goal (big picture); has an objective that describes product of research and fills in the knowledge gap/meets the need Central hypothesis links to objective, provides focus to your research, sets up the specific aims Describe how the central hypothesis was formulated (preliminary research results?) Rationale describes what is now possible after the research is conducted; this is the part that should excite the reviewers because it will clearly advance the field Specific Aims paragraph for hypothesis-driven application describes specific aims tied to the central hypothesis; aims should be brief, informative, attention-getting “headlines”; should convey why not what is to be done; global, encompassing alternatives if hypothesis tests invalid Specific Aims paragraph for needs-driven application different than hypothesis driven; should be descriptive, describe tasks to accomplish objective, what will be done “Payoff Paragraph” is expected results of research; should be at least one important outcome for each aim Final part of the Specific Aims section summarizes general impact of expected outcomes; segues to the Significance and Innovations subsections
|
|---|
Resources: | https://www.niaid.nih.gov/grants-contracts/draft-specific-aims
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133727/
https://www.biosciencewriters.com/NIH-Grant-Applications-The-Anatomy-of-a-Specific-Aims-Page.aspx https://hopkinscfar.org/resources/specific-aims-lightning-round/ |
|---|
Contacts: | cfar@jhmi.edu Most departments have a Specific Aims boot camp or seminar. Check with your department administrator |
|---|
Related Links: | Research Strategy |
|---|
We are always working to provide our faculty with current precise content. If you have brief suggestions to help us improve this page please comment below. For more extensive modifications please connect with us at BSPH.research@jhu.edu.
...