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  • Long-standing grants that can be difficult to break into without having already obtained NIH funding

  • Not a lot of downside from not being successful in obtaining funding because you still have a grant ready to apply elsewhere

  • Critically essential to sustain innovation

  • Important to instill a mission-driven theme

  • Opportunities are often only once per year

  • Recognizing the mechanism is paramount

  • Makes sense for investigators who are in their senior career stage

  • Having experience in and understanding the value and culture of centers will better prepare you to lead your own PPG

Forming a Team

  • Having board leadership is favorably recognized

  • A history of collaboration with people on your team is a perceived advantage

  • Diversity in career stages among team members is favorably recognized

  • Team members are often expected to have a track record of successful funding

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  • Reviewers often expect previous NIH funding from applicants

  • need to find a program officer who shows interest in your proposed research

  • There are often new requirements in renewal requests so being anticipatory and adaptive will serve you well

  • The proposal development typically takes a year with 4-6 months of intensive writing.

  • Hiring a grant writer can have substantial upside impact on your grant success

  • You can increase your chances of success by inviting the program officer to campus to give them a preview of the research that you are preparing

Career Impact

  • Having a PPG grant is Multigeneration mentoring viewed as a positively impactful quality that leads most to leadership positions or other desirable successes in their careers.

  • Opportunity for multigeneration mentoring

After Funding is Secured

  • Make sure you have the budget to hire a good program manager to establish good communication and cohesiveness between projects

  • Establishing working groups with representation from each core/project to foster ongoing collaboration

  • PIs should provide team-building opportunities to build connections and promote collegial interactions

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